A new wound dressing that kills all types of bacteria without harming the body Even resistant bacteria
Antimicrobial dressing:
Amferia has invented a new antimicrobial hydrogel that targets, binds, and rapidly kills up to 99.99% of bacteria upon contact. The hydrogel consists of amphiphilic antibacterial polymers mimicking the immune system. Because the hydrogel binds those polymers in place, nothing is released into the wound, making the dressing safe for the body.
Appropriate for low exuding wounds—such as post-surgical incisions and open wounds—this product can be used as a wound contacting hydrogel pad supported on the wound by a secondary dressing.
Meant exclusively for veterinary in-clinic use, in places such as surgical care units or in-patient care, all products are supplied sterile and will include instructions for use.
At Amferia, we had the privilege of interviewing Dr. Olivier Lepage, Chair of the Board of the European College of Veterinary Surgeons (ECVS), Professor of Equine Surgery, and Director of the Equine Health Center at the National Veterinary School of Lyon.
Veterinarians are looking forward to new innovations in wound healing
In this enlightening discussion, Dr. Lepage highlights the growing challenge of antibiotic resistance and the urgent need for innovative approaches to wound healing. He emphasizes the importance of developing antibacterial wound care products that offer broad-spectrum activity without interfering with the body’s natural tissue cells. Additionally, he encourages veterinarians to explore and adopt new innovations in animal wound care to enhance treatment outcomes.
This interview reflects Amferia’s ongoing commitment to collaborating with leading experts to create impactful and sustainable advancements in animal wound care.
Now sold by Orkla brand Snögg in eight European Countries
Snögg BactiDefend dressing:
Amferia technology is now available as BactiDefend Dressing within the Snögg Animal Care portfolio. BactiDefend Dressing is a sterile hydrogel formulation powered by Amferia technology, utilizing innovative peptides that mimic the immune system to bind to and disrupt bacteria without leaching harmful substances. The dressing also promotes wound healing by providing a moist environment. It is safe and biocompatible and intended for professional use only. Use on dry or low-exuding wounds. Snögg homepage >
Countries where you can buy Snögg Wound Dressing with Amferia antibacterial hydrogel:
Evidence of safety and efficacy in post-surgical wounds
Clinical case reports:
Amferia has collaborated with five leading veterinary clinics across Europe and obtained over 100 case reports on a variety of post-surgical wounds of cats and dogs.
In each case, Amferia’s hydrogel dressing enabled safe healing of wounds with no complications. Furthermore, the product could be adapted easily to the complex contours of the animals' bodies and adjusted to the required sizes.
The surgeons who used the dressings have provided excellent feedback on the usability, safety and existing evidence of antimicrobial efficacy.
Clinical case reports involving Amferia hydrogel dressings have been performed on infected chronic wounds in collaboration with two clinics in Germany and the Netherlands.
Together with Amferia, the clinics have performed five case evaluations of the Amferia hydrogel dressing in hard-to-heal infected wounds of one dog and four cats, all colonized with multi-resistant pseudomonas aeuruginosa orMRSAbacteria.
All wounds were open wounds from either trauma or chronic complications, and the patients suffered from recurring wound complications over a period of two to three months. The attending wound specialist requested Amferia dressing for trials on the patients and noted a clear effect within 24 hours, noting bio-burden reduction and formation of new granulation tissue.
100 times reduction of bacterial load in deep infected wounds
In-vivo study:
Amferia collaborated on an in-vivo infection model study with Chalmers University and the Department of Biomaterials at Sahlgrenska University.
The study results, published in ACS Biomaterials Science, describe a wound model in mice heavily infected with bacteria. The results demonstrated 100 times reduction of bacterial load in the wounds treated with the amphiphilic antimicrobial hydrogel.
This is especially impressive, given that the wound was deep and the bacterial load was extremely high. The results demonstrated the strong effect the hydrogel had on bacterial removal, from the wound in a statistically significant manner, without releasing any substances into the body.
Do you want to partner with Amferia or receive products for testing?
Contact us:
If you are interested in distributing our product, exploring a partnership, or are a veterinarian who would like to test the product and provide feedback, please reach out to us. We’re excited to collaborate and share the benefits of our innovative wound care solution with you!
Collaborate with us and receive samples for trials. Amferia is happy to provide samples of our current and upcoming products for early trials for post-surgical and other dry-to-low exuding wound applications.
Amferia and Medspray awarded Eurostars Grant to develop Antimicrobial Spray for wound care
March 26, 2024
Amferia, specializing in antimicrobial peptide-hydrogel materials, and Medspray, a spray nozzle company renowned for its expertise in micro droplet spray technology, announce our joint success in securing a Eureka Eurostars grant. This grant will support our collaborative efforts to develop an advanced antimicrobial spray for wound care.
“With the growing need for new antimicrobial technologies to address bacterial infections, Amferia’s spray will be an important tool to fight life-threatening bacterial infections in skin and woundcare. The Eurostars funding is an important enabler for Amferia to accelerate the spray product development. We are inspired by the partnership with Medspray whose state-of-the-art microdroplet spray technology will be a key success factor for delivering the Amferia technology to patients in need across the globe ” -Anand Rajasekharan, CEO of Amferia.
The Eurostars program, dedicated to fostering collaborative research and development projects among SMEs across Europe, has awarded this prestigious grant to Sweden based Amferia AB and Netherlands based Medspray BV. This partnership underscores the shared commitment of both companies to leverage cutting-edge technologies and expertise to address a pressing healthcare challenge namely antimicrobial resistance.
Titled SURPAS (Treatment of SURgical wounds with a novel, innovative Peptide-hydrogel Antimicrobial wound Spray ), this project will focus on developing the spray, initially for surgical wound care with the ambition of infection prevention. The antimicrobial spray will harness the potent antimicrobial properties of peptide materials, offering a safe and targeted approach to preventing infections in wound care settings. Coupled with Medspray’s expertise in precision spray technology, the solution aims to deliver the peptide-hydrogel as micro droplet spray with optimal coverage and penetration, ensuring rapid and effective antimicrobial action without disturbing wound healing.
Han van Egmond, CEO of Medspray — “The combination of a low energy actuated, slow moving, fine mist combined with an antimicrobial peptide hydrogel, offers a potential solution for the fast growing antimicrobial resistance of bacteria, thereby contributing to patient comfort and reducing the related treatment costs.”
The Eurostars grant provides a significant boost to the collaborative efforts of Amferia and Medspray, enabling them to accelerate the development of their innovative antimicrobial spray for wound care. Beyond financial support, the grant opens doors to collaborative opportunities, knowledge exchange, and strategic partnerships within the European innovation ecosystem.
About Amferia
Amferia has developed a technology that kills 99,99% of bacteria, even resistant bacteria, without harming the body. The innovation is based on amphiphilic hydrogel with increased clinical stability, a material created after years of research in collaboration with Chalmers University ofTechnology in Sweden. Amferia’s first product offer is a wound-care dressing suitable for dry-to-low exuding wounds. The company’s anti-microbial platform solution can also be used on a wide range of wound care products, addressing antimicrobial solutions from minor skin injuries and post-operative wounds to chronic wounds, trauma, and burn wounds. Read more about the products, team, technology and publications at www.amferia.com
About Medspray
Medspray is a privately owned company in Enschede, theNetherlands. With its 40 employees Medspray focuses on the development and manufacturing of micro spray nozzles which creates an ultra-soft mist. Medspray’s slogan is: ‘tiny technology for a sustainable future.’ Medspray aims to contribute to a sustainable world by developing innovative spray nozzles for user-friendly health and physical care products. The applications for the Medspray ranges from soft mist inhalation products that will require small and slow moving droplets up to target the lungs, as well as to the Beauty, Home andPersonal care segments like fine fragrance sprays where larger droplets or aerosols are required. www.medspray.com
About Eurostars
Eurostars is a European funding program dedicated to supporting collaborative R&D projects led by SMEs (small and medium-sized enterprises) across Europe. By fostering innovation, collaboration, and cross-border partnerships, Eurostars aims to drive economic growth, strengthen competitiveness, and promote technological advancement within the European innovation ecosystem.
Han van Egmond, CEO, Medspray BV, han@medspray.com, +31 6 51 74 60 26
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Dr. Christian Nees joins as Clinical Advisor for Amferia's Animal Wound Care
February 19, 2024
Amferia AB welcomes Dr. Christian Nees, veterinary surgeon and wound specialist, as Clinical Advisor for Animal Wound Care.
Dr. Nees is a veterinary surgeon with 35 years of experience in surgery and wound care. He was previously the head of Animal Health Hospital in Weingarten (Kleintierzentrum Weingarten), Germany. Today, he coaches colleagues and wound care specialists in veterinary care. A leading voice in animal health in Germany, Dr. Nees built and led Kleintierzentrum Weingarten as one of the best hospitals for small animals in Germany. Dr. Nees will support and advise the Animal Health team at Amferia with medical and clinical affairs and clinical testing for further development and strengthening of Amferia’s portfolio of Animal wound care products.
Anand Kumar Rajasekharan, CEO of Amferia− “It is a true honour to welcome Dr. Nees as an Advisor to Amferia. Amferia has had the privilege of collaborating with Dr. Nees on clincal testing over the last 4 years and his guidance has been important for our product development. We now look forward to jointly enable good products for addressing wound care in animal health.
Amferia AB signs major contract with Orkla Wound Care
December 4, 2023
Amferia has recently signed an exclusive Animal Health Private Label License and Purchase Agreement with Orkla Wound Care covering the Nordic region, Germany, Spain and Portugal for a period of 3 years with a possibility for extension.
Anand Rajasekharan, CEO of Amferia — “Orkla Wound Care’s market leadership in wound care will spearhead Amferia’s vision of addressing antibiotic resistant wound infections in animal health. We are inspired by this partnership, which will bring our innovation together with a leading brand to a market where there is considerable need for new solutions. Amferia’s innovation has already received strong interest and positive feedback from veterinarians from across Europe, who immediately notice the potential of our new antimicrobial material within wound and infection management.”
The joint partnership with Orkla Wound Care will enable Amferia’s technology, through Orkla leading brand Snögg Animal Care, to reach the wider European veterinary market where wound care and infection prevention is of prime importance. This has been intensified with the growing threat of antibiotic resistant infections. Amferia and Orkla Wound Care’s partnership will build on extensive data and feedback from Amferia’s clinical testing across Europe. The joint efforts will aim to market the products under the brand Snögg Animal Care from 2024.
Maria Lundman Hedberg, CEO of Orkla Wound Care— “We are excited about our collaboration with Amferia and bringing their innovative products to market under the brand Snögg Animal Care. Amferia's pioneering antimicrobial wound dressing aligns seamlessly with our dedication to providing cutting-edge solutions to veterinarians through our Snögg Animal Care range. This collaboration strengthens our position as a leader in wound care, both for humans and animals.
About Amferia
Amferia's antimicrobial amphiphilic hydrogel kills bacteria, even resistant bacteria without harming the body. The material was developed through several years of research in collaboration with Chalmers University of Technology and the first product from this technology platform is a wound-care dressing for dry-to-low exuding wounds. Amferia's innovative, anti-microbial solution can be used on wide-ranging wounds from simple skin injuries, post-operative wounds to chronic wounds and trauma / burn wounds. The WHO predicts that antibiotic-resistant infections, including those from wounds could become one of the leading causes of both illness and death over the next ten years. The material is being investigated for continuous development in several other areas, including sprays for deep wounds, and coatings for implants and a variety of catheters. Read more about the products, team, technology and publications at www.amferia.com
About Orkla Wound Care
Orkla Wound Care has a long tradition of developing, manufacturing and distributing market leading products within wound care and first aid. Orkla Wound Care is a part of the Orkla group, a public listed company on the Norwegian Stock Exchange, known for its active portfolio management targeting fast-growing consumer segments and markets.
Amferia AB is happy to announce the appointment of Ingvar Karlsson as the Chief Financial Officer. Ingvar has extensive background in financial management within a broad area including the life-science industry.
Ingvar has a solid background as the CFO from both public and private companies covering Life science and Medtech, Automotive and premium consumer goods spanning over 40 years. Today, he works both on the Board of cutting-edge life-science SME’s as well as provide service as CFO for their successful growth. Ingvar’s extensive knowledge in financial management, supply chain processes and capital planning of life science companies, will be important for Amferia’s scale-up journey in both human and animal wound care.
Anand Kumar Rajasekharan, CEO of Amferia − “It is an honour to work with Ingvar, whose impressive knowledge of the field and guidance greatly strengthens Amferia’s position as a competent and cutting-edge SME with precision in its numbers. We look forward to jointly grow the company, as we set our sights on global growth of Amferia both in human and animal wound care.
Ingvar Karlsson, CFO of Amferia − “I look forward working with the team at Amferia. The company has a very interesting journey ahead. Amferia is en route towards internationalization and distribution of its products through partnerships in multiple countries. I am glad to work with companies like Amferia improving healthcare for both humans and animals. ”
Amferia selected as one of Sweden’s best, young deep technology companies by Ny Teknik’s prestigious 33-listan
November 20, 2023
The significance of the list is that Amferia, as one among the 33 young Swedish companies is deemed to have high potential to become future growth companies. The companies selected to be on the list after rigorous evaluation by the jury, are judged to be innovative, have scalable business models and have the potential to grow quickly on the Swedish and global market.
Infections are a difficult healthcare problem, exacerbated by antibiotic resistance. Amferia’s innovative antimicrobial material is an effective, safe and sustainable way to address life threatening bacterial infections, especially within the filed of medical devices. This is equally important in both human and animal health, and we are bringing products built on our technology rapidly to the market.
The recognition by Nyteknik is an important achievement for Amferia attesting to our measured yet rapid progress of a deep technology breakthrough innovation to the clinic. And most importantly, our deepest gratitude to our collaborators in the clinics who clearly saw the need and importance of our technology in addressing an acute global healthcare threat.
Our colleague Edvin Blomstrand now holds a PhD in Materials Science from Chalmers
September 26, 2023
Amferia is thrilled to announce that our exceptional Research Engineer, Edvin Blomstrand, has successfully defended his doctoral thesis titled "Amphiphilic Hydrogels Functionalized with Antimicrobial Peptides for Wound Care" at Chalmers tekniska högskola. He now proudly holds the esteemed title of Doctor of Philosophy in Materials Science. During his PhD journey, Edvin's contributions have played a pivotal role in shaping our product development at Amferia. We couldn't be more excited to have him continue this remarkable journey with us. With him on board, we are prepared more than ever to pursue our goals, push the boundaries of innovation, and make a meaningful impact in our field.
Join us in congratulating Dr. Blomstrand on this brilliant achievement, and we look forward to the amazing things to accomplish together in the future!
Amferia’s first human clinical study published
June 26, 2023
We are thrilled to share that our dedicated team at Amferia in collaboration with Chalmers tekniska högskola has published a randomised controlled study in the Journal of Wound Care that demonstrates the outstanding antibacterial performance of our hydrogel wound dressing. We studied our wound dressing on intact human skin as a model to evaluate the speed and efficacy of the dressing to kill bacteria — and the results were truly remarkable!
By utilizing the Amferia Antimicrobial Hydrogel technology, we eradicated bacteria when placed in contact with skin within a short period of three hours.
By utilizing the Amferia Antimicrobial Hydrogel, bacteria was eradicated within three hours.
These findings demonstrate the potential of our antibacterial wound dressing to significantly reduce the risk of infection in wounds, offering new possibilities for improved patient outcomes. This study lays the foundation for our future clinical studies in human wounds.
Amferia raises SEK 15.4 million to launch innovative antimicrobial wound care dressing
January 27, 2023
The financing was raised from Almi Invest, Chalmers Ventures, and with several angel investors to support launch of Amferia’s first product, a wound care dressing with a patented hydrogel that actively combats infections and kills antibiotic-resistant bacteria.
Amferia's innovative, anti-microbial solution can be used on wide-ranging wounds from simple skin injuries, post-operative wounds to chronic wounds and trauma / burn wounds. The WHO predicts that antibiotic-resistant infections, including those from wounds could become one of the leading causes of both illness and death over the next ten years.
“I am grateful to all our committed investors: Every year, nearly 1 million people die globally because of infections caused by antibiotic-resistant bacteria and at least a quarter of those infections begin with a simple wound on the skin. Amferia's wound care solution is a game-changer and will save lives. The resistance problem is even more challenging within the animal health sector.”, says Agneta Edberg, Chairperson of Amferia.
Amferia's wound care solution is a game-changer and will save lives.
Amferia's patented material, an antimicrobial amphiphilic hydrogel, has been developed through several years of research in collaboration with Chalmers University of Technology and contains molecules inspired by body’s own immune system. The material instantly kills all bacteria (even antibiotic resistant) by binding to and disrupting their cell membranes, all without damaging the body’s own cells or entering the bloodstream. The first product from this technology is a hydrogel wound-care dressing for dry-to-low exuding wounds, while the material is also being investigated for development in several other areas, including sprays for deep wounds, and coatings for implants and a variety of catheters. In September of 2022, Amferia launched its first wound dressings for animal health in Sweden and plan on expanding across Europe during 2023. In parallel, the company is preparing to file for regulatory clearance in the US for human health.
The wound care market currently generates sales for over US $ 2 billion globally with a projected CAGR of 5 %. However, existing alternatives on the market often contain antibiotics that carry the risk of causing resistance or antiseptics that may harm body cells and negative environmental impact.
We already have our first product on the market for animal wound care in Sweden
“The investment enables us to perform three key tasks: scale up and launch our products for animal health in Europe, file for FDA clearance of the application for human health and thirdly initiate more clinical studies in both market segments. This ambition is supported by the fact that we already have our first product on the market for animal wound care in Sweden”, says Anand Kumar Rajasekharan, CEO of Amferia.
Pre-clinical research on new antimicrobial spray and coating technology published
January 26, 2023
Amferia announced today that it has, in collaboration with Chalmers University of Technology, published two important scientific articles in peer-reviewed journals that describe the pre-clinical studies of its platform technology, Amphiphilic Antimicrobial Hydrogel as sprays and coatings for various medical device applications.
Amferia’s platform technology is an amphiphilic antimicrobial hydrogel material that can rapidly bind and kill all types of bacteria, even resistant bacteria, without harming the body. In an effort to enable further applications of this material, Amferia collaborated with Chalmers University of Technology to test and develop the patented technology as sprayable formulation and as coatings fight off bacterial infections in medical devices.
Today, the extensive pre-clinical data from this research has been published in two scientific articles in peer-reviewed journals*. The research was built on the formulation of the Amphiphlic Antimicrobial Hydrogel as small discrete particles, which were then further developed as sprayable form for wound care and as a coating on existing materials like silicone catheters. The results from these studies show powerful antimicrobial effect, safety to human cells while being stable in biological environments such as serum.
The material has been shown to be effective against many different types of bacteria, including those that are resistant to antibiotics
Martin Andersson, Professor at Chalmers University and Co-founder of Amferia − “Our innovation can have a dual impact in the fight against antibiotic resistance. The material has been shown to be effective against many different types of bacteria, including those that are resistant to antibiotics, such as Methicillin-resistant Staphylococcus aureus (MRSA), while also having the potential to prevent infections and thus reduce the need for antibiotics,.”
The research was undertaken based on the strong potential of Amferia’s technology, but also based on a clear need from the human and animal health care system on fighting infections in the context of deep infected wounds as well as for various medical devices such as urinary catheters. Amferia and Chalmers will continue to collaborate on this research and are planning to further study the use of the new formulations in clinical settings, both for human and animal care.
We are seeing the great potential of our technology going beyond wound care into the realm of broader medical devices
Anand Rajasekharan,CEO of Amferia − “This is an important achievement for Amferia as we are seeing the great potential of our technology going beyond wound care into the realm of broader medical devices such as coatings and sprayable systems. Our current product is a wound dressing and we look forward to follow-up the same with these pipeline products that will have a stronger impact for addressing antibiotic resistance.”
Agneta has a solid background from the global Life science and Medtech field spanning over 30 years in leading roles such as; Sales &Marketing Director of Pharmacia (Pfizer), Senior VP and CEO of Mylan NordicPharmaceuticals, CEO of NM Pharma and more recently as the COO of Bactigaurd that manufactures a variety of antimicrobial device. Today, she works on theBoard of cutting-edge life-science SME’s guiding the companies for future success. Agneta’s extensive knowledge in the life science industry will be important for Amferia’s scale-up journey in both human and animal wound care.
Anand Kumar Rajasekharan, CEO of Amferia − “It is an honour to work with Agenta, whose impressive knowledge of the field and guidance greatly strengthens Amferia’s position as a competent and cutting-edge SME. We look forward to jointly achieve the upcoming key milestones such as the first product launch for animal health, FDA and CE regulatory processes for human health and establishing a successful sales and marketing foundation for Amferia.”
Agneta Edberg − “Amferia is a company every board person wishes to work for. The technology offers a paradigm shift in wound care with nontoxic properties still killing bacteria, even the resistant ones. In a world where antimicrobial resistance is an increasing challenge to humanity, I am grateful to be a part of reducing that threat”
