For decades, we’ve known that antimicrobial peptides are potent killers of bacteria. Peptides carry a positive electrostatic charge, which naturally attracts the negative charge bacteria carry. Once attached, the knife-like structure of peptides puncture bacterial membranes, killing the cells.
What hasn’t been known—until now—is how to protect vulnerable parts of the peptide from natural enzymes in the human body. In nature, peptides are fragile molecules. Enzymes can destroy them in seconds. To be effective bacteria killers, peptides need protection.
To be effective bacteria killers, peptides need protection
Amferia solves that problem with an innovative, patented hydrogel platform that encases peptides in a solid gel, leaving only the knife-like structure free to attract and puncture bacterial cells.
Because peptides kill bacteria in a physical—as opposed to chemical—process, Amferia products kill even bacteria that has become resistant to antibiotic drugs.
Amferia’s hydrogel stabilizes and protects the peptides for up to five days in biological environments, keeping them actively killing bacteria that entire time. Amferia harnesses peptides in a safe, stable, non-toxic and clinically applicable form, allowing them to kill bacteria without harming anything else in the body.
Amferia’s proprietary antimicrobial technology consists of bio-inspired and amphiphilic antibacterial polymers that target, rapidly bind and kill up to 99.99% of bacteria upon contact—including numerous strains of antibiotic resistant bacteria like MRSA and MDR E. Coli.
The material is selective and targets only bacteria while being entirely non-toxic to the human and animal body.
Now, Amferia has developed this platform into its first in-market product—wound dressing for animal care. Ultimately, the goal is to bring this technology into the market as new and effective products to treat patients at risk of acquiring dangerous skin and wound infections.
Amferia’s approach to killing bacteria
- 1. Binds and kills bacterial loads in seconds—including antibiotic resistant bacteria
- 2. Highly potent and targets only bacteria
- 3. Completely harmless to human and animal cells
- 4. Does not release any antimicrobials into the wound environment